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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ea3cae72ddd6589e3f75d81a0f8f68599f2f46bb8a27399315a0557aafee70f' 
  AND token = '7TtgUCL4H0wEl5U5tRqAHDHk9TwCj1rYfc711M6cOqs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}