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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8ca5c12b78ab6da633d1b80d7871fa2036387bff5a6045c6a733acc218495d0' 
  AND token = 'SQIAZfHUTiZ/mTKIWMMhmpk7VXWBKXLavdMZO61b1G0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}