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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf7739b0d81bd4b7c79e573b5be6c7ad69837a893060567732e073186f96cc09' 
  AND token = 'cI0F/0Iu+KaQ0UFfsX534THf/4Iw20H74knwhpRBHDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}