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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '469bbbf620d9b1df73cbfcae3fc2020e81e31cc39b278cb6943efc31f18a3180' 
  AND token = 'K5zNqOLeZE7hmkO9ws6QD99ATB4PBE6DBx5bRJxZU+k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}