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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a3d7d76e0a2be52c1e922e40e3b07f5cfd295e64dbf5f52f7f11ace0f2324c09' 
  AND token = 'jQs7+xcrkzXTiu9/gWc6GQNQCowJ8dxUv6mzVt0G1Bk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}