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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e9586a6f176bd14889128a571c5fabbff502418f0275224e0d8f703af8c06c9' 
  AND token = 'j9/2pTKBREbyfZ0+2HH/lFsf21IW4W9GZqayfXuuxYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}