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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '21848863837fe81b8971600e23560ac9170825be18fb2afe1c8c053d7046e1ae' 
  AND token = 'KVePGR7tgeUCdZV8Je6OZl1+MVJegJuTcRgxG8vVPUw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}