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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1d320cc31deb962a57b52a187d2b4319a91ce69cac12bc11390a4f1d1da0bba0' 
  AND token = 'AJEe4Mfbv8WLvbr9Qa+2/ORX2aOj/K4JdzQB1DM8DEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}