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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '107dd32af9e98c7e8ab76d13361eeaaa8d388a48e58d5fcfbd9dc1fdae51179f' 
  AND token = 'J/FG1LoS9yzDA6qwlRT3qzVP8tAIe6U3CzVLixyB/y4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}