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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a4abff3c9fe30a9b0a2af7b1133850dd4818e4ef883fe6640964335d9e558d7' 
  AND token = 'DTq7XQCNGY9jK4rSf29Jk/h3dE+YLayxfPQNT8bfdOM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}