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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '77de0adb83bd51a0974f64208f259289652ee9e600fbd39d83131bed75a31e14' 
  AND token = 'TngDHZ8w4S+hoYYPb2Z1h8jCekrdbjZEjNb79C7ndc4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}