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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f7981cc745255623e5be1e4ae409e79987be2e2891182f54e434a24f2015bfc5' 
  AND token = 'So3C3kRrOnEgSoczeY8tILFBgvKss3ApuIzRPwF1RY8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}