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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b6b58ecab2f2ef67b354d777df216dc4c4b85f66ee1b9a91a29c6dc0065199' 
  AND token = '54r1b11naJyE0w+6R6Qipm+P3rgPNXODm8G0SByz51c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}