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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a0453a1b9341e7bbe6c23d5b7b0bfad21316f80f224dc3e31c18066b924dacb' 
  AND token = 'nzNp8xDLGywe/AJaEECc9+8huaJos/BdDQkoist9zcU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}