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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e61b2293e99f154b2fc3129721c103052d062f3013a19cc0787fbe5f76de447' 
  AND token = 'MNqTQ+fNjD1RRMbOkqvnIXPCQi2pz97maLE8s1t563Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}