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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efd757ed1bed47c006bf39e3a570b92d04de75848baf44b57cc21aba75eeda7f' 
  AND token = 'GZ/D2ZQSW9G7E21tfegX8NaeFFQ4cvQhdp+hKVuAKJ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}