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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74b6ab101f8d259800fcccef03d262806eee46f19c070ec2631899e4bfb0f427' 
  AND token = 'Y8XtN8KK40FUhTi2JllFs8zPs2P2DzNIBtZpppZ4o4I=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}