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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f820b7fd77063b0834d841e16fa9d4cc74b68f4d66ead20daa768a2d0a23effb' 
  AND token = 'WOZpfJ+Zzgay7OHt/XL1JvhM/No7b1EC/SlEm6KGER4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}