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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ffee2cf8c1359a692ffc18baf3d16c63b9efa3cbbeea36875a3f6011e71174ca' 
  AND token = 'U+XE47lNe/jtZ1nIgF0DzHs90nkmcUrNMpdEmvSo21g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}