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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05b5322cc4defb588ce35a8a8226d96a8d09fa7c1df44fbcd00d0a9b7f3150f3' 
  AND token = 'XyqtjS/JJwmjjqWeka9mStvY68SzYOUFD0HKY08wPEs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}