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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2ba317c08f0dfa4efb8711a7f3be30481ba5afe9bf7541b92615ed5e9dfe6995' 
  AND token = 'JI5WpT7fFU02FKOZ6alS0a6y3NaR/nkkZLz7xnVDUx0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}