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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0caccff8d33e495cba2eea0fc04d1375907d42e0857a1e0d282e365d4caad92' 
  AND token = 'CZG8k1zOtNVaKlzp/46M7LJ6Id/mmA4FLiDvO6JgD4s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}