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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c5eca16005c80c90ded8add5a711191e6a86cd9097e7a5ec3bc080d68ed9e187' 
  AND token = 'MMxSxJbi+pEx6oxmOVUr2in8ZSabrwYeNxe0Pap6o/0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}