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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ddf92cf1c260ea24a3a3af75d673348f3f58defa1b9c0de3d33a26ef1945f22' 
  AND token = '27XUVINus4aCHeRQ828hpqWNoup7K8EqmTGWyvg7af0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}