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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '365415f754947064214c8bd7bbdad3c4141e6b1dcec159c933a9039ebf15cfaf' 
  AND token = 'Iivxh5JZQ65q0dU57MZUeECnD3GbbrGH3KGjG/ms6Ys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}