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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b887109a9af7df130ae6a4e28a38302a0e83856a9530846a5464e2080c76b82' 
  AND token = 'G4VWSOp7Hc9R92JWb0IeWyxbDORqoANW2HaC/PcLy0Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}