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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ce8812aab85131fd8f42b5e2def25840e44867d4b7e542ab5c589e333cdc1f7' 
  AND token = 'pzBDHUHt8ZpjJ9rIAXYxn8arb+oDPP0Z3lQpowx3kIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}