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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6ec42f432c8ac3c2442edd87c7e95b01377b50b7575d133f839ede8101fd73c7' 
  AND token = '/pT+MA95GAeb1JY94tTbFVihUc/BeZgFkeMvm0BZwGY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}