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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8ae9aa4b0c4bc59360fa7619c65c2c879453d02a279db1e0fda0d90efbed28a8' 
  AND token = 'ML7NhG4uQFHA/QmKY/05MAno4bR1C0IgcgfDH2KPlf8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}