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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dfcd0cd9854fef470aee011569f920ac0e88d33d633e4146323ebe1c28a2c991' 
  AND token = 'Q6bxX8Oe0dfHHavQaVC1GNHb1Tax+Qjn4GyrkoCz+QM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}