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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '61a1d9ba48caf8d74e2bcca38549e37b364cd6132b28cfef2c8a4153761b33a3' 
  AND token = 'POMwCVVutFxbCv5QNsyGaZZOz/sAMZ33N6Gx1IYrTB0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}