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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c9d3c85e54196e499657ff03fca0a45a9ecf14ae2df84bdeaa75e04ea37dcb85' 
  AND token = 'ktDQX2km4RY0Mv6xDX3jsgI8XaB1fxPg/Tk67xtbX0Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}