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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '51dd2127ca2f3f13e847afb41d1c1d0cb57a12e4f05a63aa525049a99e0b731d' 
  AND token = 'gyC3y9nWdir3GBZwgmTFrbq2FwM7J9Qwu3UbBXyvO1k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}