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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2121fcf06491feb21c0cd28e1969fb748595a27db1a29e96f5302b91fdccd2ea' 
  AND token = 'pg+pg2glEUMDfNHUkdINi3NZLnttUr+UPVVuuptf7Q0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}