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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0e44e326ce0cf8abdad98cce13eb09074d43b4d0932dc6d860b344a1362073f7' 
  AND token = 'iXdRLN7ssL/Vc/8r7sbh8IVB0FtnCE9khzypA+r7rfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}