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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05853f1e4bfb112f0521f0faa531becc58bfe39b91485b9d05cd406fbf68d6e2' 
  AND token = 'mPwuHyTSdnwNp/F2mXk9dRrBEnatGxI5ehiCSFv6Gx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}