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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e98e53ccbefbe043c1e518f7a89f50b020926e0984a4e1265a59dc8d6fe01000' 
  AND token = 'npLc9q8dejFL48+ak8rJUTYk6FJMBWMIpa0780Ulczw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}