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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d78790a9cba3546984fea15c9b0c75ebb841a9de625111e5b55e6fd282e4405' 
  AND token = 'tSanjihDIhBcFZVqip4Kr9t7GUAUbZp7eZ18O0nRF3g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}