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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8fc5bb893c504ac4a656f7a8a5bf767ecdabad1282765ddd1e3fc54d56b339b' 
  AND token = 'EO8Dl1aSf81Md9eWYLFHefrnWVC55ADmP35uyrljRZw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}