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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '90c759cbbf40e2995fadde4aa0404298ddf94a432bea7f0ec5da970251ac77ec' 
  AND token = '0FJ1I3LyH6UH5reXbLIVJFfkbJiKOJuLDFwmkvdIkfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}