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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cedc67120aa0a0dfce47eec6c3300a8957a000835efab5395fddf660d2bb421' 
  AND token = '95ZuV3HF4kS5NVTB0dP+abxvv/UTb38OJdTgwQCQSe4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}