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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b2c54c967be4d4fcd444e0b4f2ff30d2f82d96ff140689d03f35a7e98125cee' 
  AND token = '8yZjFt6iA4I2HbhoPq1in+k8Mymt+cRlkIDu9QLLqlM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}