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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '05dd24dd993ceae97431a5b83d2ee90b0b3bbbc3c71cbcdc3fdecd64d38f1364' 
  AND token = 'mcD2exF7Nzzrnozbem0F+Nt8dqSATzvW1xkTX7GJGV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}