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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '06d9f27261139bc74f75c48ea60338fcd09cebdacc6c97b2f91e911a891a827c' 
  AND token = 'LEqE+bta4X3EpGUXoE2/k3rUeiQX04ZFMEmPSLCRYAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}