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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9d0c7d23e75fa2d1e1b0ac4f9d4309999001ad37cf7cdb21e5d2720e02447707' 
  AND token = 'D/UAolNQ2MyZ3TRbLvRdgBuHbVSMCs7VAS2jWGM6rmA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}