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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b597977e3ab16a44bdb5cab145034028efb4b40e3b921f19fc646a8965df3225' 
  AND token = 'wbnOL0OT+gIGKY4gVP//fZ/01/Q8ceRNLpj6GtM8ePA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}