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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '57dd3d07f8dfd6a12c377b4d4a568e394a094b8650eae65ae6edab2f4a9075d8' 
  AND token = 'xrzpM9zKyg5/3LHSQRiIZPiBxqAezAc2kt3ck6QSIp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}