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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2b1cf00008723f9c27d8e48d59d77743f6c7b85e01c7ec0a18e02a70809cd51' 
  AND token = 'HRUlXmUmDZa5CQX5B2NkVmrEYIA+bH9kC07PIVHbrgw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}