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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '189a2ed1cad990b8af747351d6a9b851d37cd7b910e41993c426a3db12c3ba34' 
  AND token = 'pcNrqLS++Myc2UlqOksZhCC4flHffLKyoMjTcVM45WM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}