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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b651cc87e6a3563083f76f1618d30d3fb3b4dd61f616428fc8cbe1335987f0b' 
  AND token = 'McEGoV5brDDKxW4V1lPcTDLW4qDCCHwbOTumXfJK5V0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}